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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24C All Species: 23.64
Human Site: S937 Identified Species: 37.14
UniProt: P53992 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53992 NP_004913.2 1094 118325 S937 Y V R Q L V T S M D V T E T N
Chimpanzee Pan troglodytes XP_001145058 1094 118246 S937 Y V R Q L V T S M D V A E T N
Rhesus Macaque Macaca mulatta XP_001104565 998 107625 D849 L N C V L K S D V L Q P G A E
Dog Lupus familis XP_850963 1096 118584 S939 Y V R Q L V T S M D V A E T N
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 L937 Q P L V H L M L T T H P S L Y
Rat Rattus norvegicus NP_001102926 1095 118506 S938 Y V R Q L V S S M D V A E T N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513100 1030 112379 L881 M G V A D T Q L F F Y P Q L L
Chicken Gallus gallus XP_421617 1147 124543 S990 Y I R Q L V T S M D V A E T N
Frog Xenopus laevis NP_001087832 1126 123503 A969 Y I R Q L V S A M D V A D S H
Zebra Danio Brachydanio rerio XP_700597 1315 142554 A1160 Y L R Q L V S A M D V A E S H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392952 1276 140829 T1118 F V M Q A V A T M P I S I S V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783728 1150 123558 S993 W L M Q T V L S M D V V S T H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M081 1080 116273 T925 N Y V S S L S T P L A I P L V
Baker's Yeast Sacchar. cerevisiae P53953 876 98925 F727 D E V G L P D F E G K T V L P
Red Bread Mold Neurospora crassa Q7S4P3 950 103512 P801 L Y S L H D M P D N A G I P D
Conservation
Percent
Protein Identity: 100 99.5 86.9 94.8 N.A. 26.9 92 N.A. 51.9 75.4 69 59.5 N.A. N.A. 44.5 N.A. 52.6
Protein Similarity: 100 99.7 87.9 96.1 N.A. 45.8 94.4 N.A. 66.2 82.3 78.1 69 N.A. N.A. 59.4 N.A. 64.3
P-Site Identity: 100 93.3 6.6 93.3 N.A. 0 86.6 N.A. 0 86.6 53.3 60 N.A. N.A. 26.6 N.A. 46.6
P-Site Similarity: 100 93.3 20 93.3 N.A. 6.6 93.3 N.A. 6.6 93.3 93.3 93.3 N.A. N.A. 60 N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. 33 22.4 30
Protein Similarity: N.A. N.A. N.A. 49.3 41.1 47
P-Site Identity: N.A. N.A. N.A. 0 13.3 0
P-Site Similarity: N.A. N.A. N.A. 20 13.3 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 7 0 7 14 0 0 14 40 0 7 0 % A
% Cys: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 7 7 7 7 7 54 0 0 7 0 7 % D
% Glu: 0 7 0 0 0 0 0 0 7 0 0 0 40 0 7 % E
% Phe: 7 0 0 0 0 0 0 7 7 7 0 0 0 0 0 % F
% Gly: 0 7 0 7 0 0 0 0 0 7 0 7 7 0 0 % G
% His: 0 0 0 0 14 0 0 0 0 0 7 0 0 0 20 % H
% Ile: 0 14 0 0 0 0 0 0 0 0 7 7 14 0 0 % I
% Lys: 0 0 0 0 0 7 0 0 0 0 7 0 0 0 0 % K
% Leu: 14 14 7 7 60 14 7 14 0 14 0 0 0 27 7 % L
% Met: 7 0 14 0 0 0 14 0 60 0 0 0 0 0 0 % M
% Asn: 7 7 0 0 0 0 0 0 0 7 0 0 0 0 34 % N
% Pro: 0 7 0 0 0 7 0 7 7 7 0 20 7 7 7 % P
% Gln: 7 0 0 60 0 0 7 0 0 0 7 0 7 0 0 % Q
% Arg: 0 0 47 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 7 7 7 0 34 40 0 0 0 7 14 20 0 % S
% Thr: 0 0 0 0 7 7 27 14 7 7 0 14 0 40 0 % T
% Val: 0 34 20 14 0 60 0 0 7 0 54 7 7 0 14 % V
% Trp: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 47 14 0 0 0 0 0 0 0 0 7 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _